In the Cart: 0 Item(s) - Current Total: $0.00 - View - Checkout

Thorne Research

Indole-3-Carbinol

To support estrogen metabolism
  • maintains optimal 2-hydroxy/16-hydroxy estrogen ratios
  • found in cabbage family vegetables, it's a source of DIM
  • nutritional support for liver detoxification
  • made without flowing agents that can inhibit bioavailability


60 Capsules

Online Price: $27.60
Save to my Wish List
Indole-3-Carbinol
Indole-3-Carbinol
The products displayed on this website are not shown to actual size and may vary due to label changes.
Indole-3-carbinol (I3C) is a compound found in high concentrations in vegetables of the Brassica family, including broccoli, cauliflower, Brussels sprouts, and cabbage.

As a dietary supplement, I3C provides key nutritional support for liver detoxification. It also plays an important role in supporting female reproductive health. The majority of ingested I3C is absorbed in the small intestine as diindolylmethane (DIM), which is thought to be the primary contributor to I3C's beneficial properties. DIM has been shown to selectively bind to estrogen receptors and may act as an estrogen antagonist at physiological concentration.

In the liver, I3C promotes the metabolism of estrogen and increases the ratio of 2-hydroxy estrogen to 16-hydroxy estrogen. The 2-hydroxy estrogens, less active than the 16-hydroxy estrogens, generally are eliminated more rapidly from the body. One prospective study found postmenopausal women with the most favorable urinary 2:16-hydroxyestrone ratio were most likely to maintain good female health.

Preliminary studies have examined the efficacy, safety, and optimal supplementation of I3C. A 12-week phase I trial conducted on 17 women found a 66-percent increase in urinary 2:16-hydroxyestrone ratio with administration of 400 mg I3C daily.


Take 1 capsule one to two times daily or as recommended by a health-care practitioner.
One Capsule Contains:
Indole-3-Carbinol / Diindolylmethane (DIM) complex 200 mg.


Other Ingredients: Hypromellose (derived from cellulose) capsule, Microcrystalline Cellulose, Leucine, Silicon Dioxide.

ALLERGY WARNINGS
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

EXCIPIENT FREE
This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates.

PREGNANCY WARNING

If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS/CONTRAINDICATIONS
There are no known adverse interactions or contraindications at publication date.




All prices are subject to change without notice.

This Web site is not to be used as a substitute for medical advice, diagnosis or treatment of any health condition or problem. Users of this Web site should not rely on information provided on this Web site for their own health problems. Any questions regarding your own health should be addressed to your own physician or other healthcare provider.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.