required by law to follow up for an appointment every 6 months or as directed by their doctor.
Testosterone therapy is widely prescribed for postmenopausal women. No testosterone product, however, is FDA approved for use in women. Testosterone production is critical for women. Testosterone is a major precursor for estradiol production, and it acts directly on androgen receptors throughout the body. Testosterone levels decline with age across the
reproductive years; by the time women reach their late 40s, their blood
testosterone levels are approximately half what they were in their 20s.
Testosterone may also be important for the
maintenance of bone and muscle mass. Observational studies have reported that low
serum testosterone is associated with lower bone mineral density and increased
fracture risk in postmenopausal women.
a perceived link between increased testosterone and cardiovascular disease,
most studies do not show that higher testosterone contributes to
cardiovascular disease risk in postmenopausal women. A large study has reported an increased
risk of coronary heart disease events in women who had low levels of total and
Testosterone improves commonly reported sexual
problems, such as diminished sexual desire and arousal, pleasure, and overall
Research evaluating the effect of testosterone
therapy on cognitive performance in postmenopausal women is under way.
*American Society for Reproductive Medicine Volume 20, Number 2 - May 2012
Transdermal application of Testosterone is the preferred route but yet to be
FDA approved. Women require a much smaller dose than men. Proper monitoring of lab tests is important
to establish correct dose and prevention of any above laboratory
SIDE EFFECTS of Testosterone replacement for Women may include, but are not limited to:
- hair loss
- voice deepening,
- enlargement of the clitoris,
- hair growth where a woman does not want
- some studies also show an elevation
of LDL and lowering of HDL.
- oral testosterone can increase risk
of liver tumors and cholestasis but this is not shown with transdermals.