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I3C Plus

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I3C PLUS contains the cancer fighting substances indole-3-carbinol and diindolylmethane, as well as betaine hydrochloride and ascorbic acid (which create the acidic conditions necessary for these cancer fighting substances to function optimally).
I3C Plus contains no magnesium stearate and is suitable for hypersensitive individuals.
120 Capsules
$26.95 List Price

$25.00 Online Price


Hundreds of research studies conducted over the last 25 years have clearly shown that indole-3-carbinol (I3C), a substance found in cruciferous vegetables (e.g., broccoli, cauliflower, cabbage, and brussels sprouts) has powerful abilities as a cancer fighter. Some of these studies have shown that I3C itself is very unstable and under the acid conditions found in the stomach breaks down into a number of metabolites that effectively fight cancer.
According to the studies, diindolylmethane (DIM) is the most active and effective metabolite of I3C. Animal studies in which stomach acid conditions were bypassed indicate little effectiveness when I3C is taken by itself. I3C Plus thus includes betaine HCl (a form of hydrochloric acid) and ascorbic acid ensuring that the I3C will break down into a full range of metabolites.
One of the major applications of I3C Plus is as a preventive for breast cancer. It has been shown that in this application I3C and its metabolites can cause the breakdown of estrogen into its 2-hydroxy form (a cancer preventer) rather than the 16-hydroxy form (a powerful cancer promoter). Some studies have shown that I3C and its metabolites can prevent the metastasis of breast cancer.
As a dietary supplement take 2 capsules twice daily with food, or as directed by a health care professional.
Female patients who are prone to headaches and continue to have hot flashes and nightsweats on Estrogen replacement have found that if they take DIM (Indole-3-Carbinol / Diindolylmethane (DIM)complex) at the same time they take their Estradiol or Biest, they NO longer have hot flashes, sweats and headaches. 

This may be due to I3C and DIM increasing C2 Hydroxylation of the estrogen in favor of C4 and C16 Hydroxylation which also decreases breast cancer risk. 

If you are continuing to have these menopause symptoms while on Bio-Identical Estrogen therapy, try taking Indole 3 Carbinol by Thorne. 
1 capsule provides the following percentages of the Daily Value:



% Daily Value

Indole-3-Carbinol (I3C) (>99% pure)

60 mg


Diindolylmethane (DIM) (>99% pure)

60 mg


Betaine HCl

60 mg


Ascorbic Acid (Vitamin C) (>99% pure)

30 mg


* No established Daily Value
I3C Plus only contains the highest-quality indole-3-carbinol, diindolylmethane, betaine hydrochloride, ascorbic acid, gelatin (capsule), microcrystalline cellulose, silica, and magnesium trisilicate.

I3C Plus does not contain wheat, rye, oats, corn, barley, gluten, soy, egg, dairy, sugar, yeast, salicylates, wax, preservatives, colorings, or artificial flavorings.

Keep this product out of the reach of children. Store in a cool, dry place.

All prices are subject to change without notice.

This Web site is not to be used as a substitute for medical advice, diagnosis or treatment of any health condition or problem. Users of this Web site should not rely on information provided on this Web site for their own health problems. Any questions regarding your own health should be addressed to your own physician or other healthcare provider.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Schedule an appointment call : 717.832.5993

Schedule an appointment CALL : 717.832.5993

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