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I have spent decades studying many unconventional treatments and healing philosophies. I have gathered a collection of resources...  Read More

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IV Vitamin C and Doxycycline in treating cancer by targeting Cancer Stem Cells

Conclusion: Numerous functional studies have now directly shown that mitochondria are an important new therapeutic target in cancer cells. Since Doxycycline, an FDA-approved antibiotic, behaves as an inhibitor of mitochondrial protein translation, it may have therapeutic value in the specific targeting of mitochondria in cancer cells. However, in this paper, we have identified a novel metabolic mechanism by which CSCs successfully escape from the anti-mitochondrial effects of Doxycycline, by assuming a purely glycolytic phenotype. Therefore, DoxyR CSCs are then more susceptible to other metabolic perturbations, because of their metabolic inflexibility, allowing for their eradication with natural products and other FDA-approved drugs. Thus, understanding the metabolic basis of Doxycycline-resistance has ultimately helped us to develop a new synthetic lethal strategy, for more effectively targeting CSCs.

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Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs)

 

Another study
Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs)

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Dr. Adrian Hohenwarter MD is the leading Alternative Medical doctor in Central PA. As an Integrative doctor focusing on complementary alternative family medicine since 1989, he offers extensive knowledge in Bioidentical Hormone Replacement Therapy for men and women, Detoxification with Intravenous IV Therapy including EDTA Chelation Therapy | Nutritional IV Therapy | Myers Cocktail and IV Glutathione, Nutritional Counseling, Cancer Support, Natural Thyroid Replacement Therapy and professional grade supplements at low prices. We service patients in Palmyra PA, Hershey PA, Harrisburg PA, Lancaster PA & Reading PA. In addition, we attract patients from Baltimore MD, New Jersey, New York, Washington, Ohio and as far away as Texas and Florida. We offer natural approaches but also offer traditional medical services for your entire family from children to adults of all ages.